Author

Manuel Tschan

F. Hoffmann-La Roche AG

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Annika BlankiD· 1 shared Carmen S. M. Yong· 1 shared Elisa D’ArcangeloiD· 1 shared Lauriane CaboniD· 1 shared Matthias P. LütolfiD· 1 shared Melanie Obenloch· 1 shared Nitya NairiD· 1 shared Tania JetzeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Annika BlankORCID

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1 paper

Recent·Most cited

Human lung explants as a predictive platform for evaluating the on-target, off-tumor toxicity of T cell bispecifics

Manuel Tschan, Tania Jetzer, Melanie Obenloch, Annika Blank, Carmen S. M. Yong, Nitya Nair, Lauriane Cabon, Elisa D’Arcangelo, Matthias P. Lütolf

This paper establishes a human lung explant model to quantify T cell bispecifics' on-target, off-tumor toxicity by measuring T cell activation and epithelial cell killing.

iScience · Sep 26, 2026Peer-reviewedCancer Biology