Author

Marcel Misak

University Medical Center of the Johannes Gutenberg University Mainz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:Hi-C· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Azza Soliman· 2 shared Ruxandra A. LambutaiD· 2 shared Susanne GerberiD· 2 shared Daniel PiehiD· 1 shared Jan PadekeniD· 1 shared Jannik Foerster· 1 shared Jasper J. MichelsiD· 1 shared Jennifer WinteriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPathology

Azza Soliman

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2 papers

Recent·Most cited

16p11.2 Copy Number Variation Alters Genome Architecture and Transcriptional Regulation During Neurodevelopment

Marco Bertin, Marcel Misak, Mohit Navandar, Azza Soliman, Ruxandra A. Lambuta, Roshan Tumdam, Jennifer Winter, Matthias Linke, Stephan Käseberg, Malin Dewenter, Katalin Komlósi, Lea Zografidou, Oliver Tuescher, Sergiy Davydenko, Daniel Pieh, , Susann Schweiger

This study investigates how 16p11.2 copy number variations affect genome architecture and transcription during neurodevelopment, finding both local dosage effects and broader chromatin changes.

bioRxiv · May 8, 2026 · PreprintPathology

Correcting Preprocessing Bias in Sparse Chromatin Contact Data Enables Physically Interpretable Reconstruction of Genome Architecture

Stanislav Sys, Marcel Misak, Azza Soliman, Rosa Herrera-Rodríguez, Ruxandra A. Lambuta, Stephan Weißbach, Michael Wand, Karin Everschor‐Sitte, Susann Schweiger, Jasper J. Michels, Jan Padeken, Susanne Gerber

The paper identifies preprocessing bias in chromatin contact data and introduces a framework to correct it, enabling physically interpretable genome architecture reconstruction.

bioRxiv · Apr 2, 2026 · PreprintBiophysics