Pre-plasma cells proliferate and differentiate at the germinal center-medulla interface of antigen-draining lymph nodes
Laurine Binet, Lucas Bremond, Marius Duparc, Chuang Dong, Léa David, Noudjoud Attaf, Laurine Gil, Matthieu Fallet, Thomas Boudier, Bertrand Escalière, Lionel Chasson, Myriam Moussa, Lucas Bertoia, Samuel Origlio, Sylvain Bigot, , Pierre Milpied
The paper tracks GC-derived B cells in lymph nodes to identify PrePC cells and their transition to plasma cells, revealing spatial and transcriptional changes during differentiation.
bioRxiv · Jul 26, 2024 · PreprintImmunology