Author

Sylvain Bigot

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Bertrand Escalière· 2 shared Laurine Gil· 2 shared Mauro GayaiD· 2 shared Abel Lopez Hernandez· 1 shared Camille Pierini-Malosse· 1 shared Carole Siret· 1 shared Chuang DongiD· 1 shared Cyrille MionnetiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Bertrand Escalière

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2 papers

Recent·Most cited

In vitro-generated murine monocyte-derived dendritic cells habor a unique identity compared to other mononuclear phagocytes, largely conserved with their human and putative in vivo counterparts.

Abel Lopez Hernandez, Laurent Hannouche, Laurine Gil, Sylvain Bigot, Laurence Borge, Mark Barad, Cyrille Mionnet, Camille Pierini-Malosse, Romain Fenouil, Bertrand Escalière, Jean Descamps, Sergio Villazala Merino, Mauro Gaya, Pierre Milpied, Marc Dalod

This study generates a transcriptomic atlas of in vitro-derived mononuclear phagocytes to clarify the identity of moDCs and their in vivo counterparts.

bioRxiv · Oct 13, 2026 · PreprintImmunology

Pre-plasma cells proliferate and differentiate at the germinal center-medulla interface of antigen-draining lymph nodes

Laurine Binet, Lucas Bremond, Marius Duparc, Chuang Dong, Léa David, Noudjoud Attaf, Laurine Gil, Matthieu Fallet, Thomas Boudier, Bertrand Escalière, Lionel Chasson, Myriam Moussa, Lucas Bertoia, Samuel Origlio, Sylvain Bigot, , Pierre Milpied

The paper tracks GC-derived B cells in lymph nodes to identify PrePC cells and their transition to plasma cells, revealing spatial and transcriptional changes during differentiation.

bioRxiv · Jul 26, 2024 · PreprintImmunology