Gfi1-expressing Paneth cells revert to stem cells following intestinal injury
Min-Shan Chen, Yuan-Hung Lo, Joann Butkus, Winnie Zou, Yu-Jung Tseng, Hsin-I Jen, Shreena Patel, Andrew Groves, Mary Estes, Ergun Sahin, Mark Frey, Peter Dempsey, Noah Shroyer
This study shows that Gfi1-expressing secretory cells can revert to stem cells after intestinal injury, with PI3kinase/AKT and WNT signaling enhancing this process.
bioRxiv · Jul 16, 2018 · PreprintCell Biology