Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis
Katy C. Liu, Aleksander O. Grimsrud, María Fernanda Suárez, Darren M. Schuman, Michael Lucio De Ieso, Megan N. Kuhn, Ruth A. Kelly, Rose Mathew, Joan Kalnitsky, Matthias Mack, Florent Ginhoux, Violet Bupp-Chickering, Revathi Balasubramanian, Simon W. M. John, William Daniel Stamer, Daniel R. Saban
The paper identifies resident tissue macrophages as critical for maintaining intraocular pressure homeostasis by regulating extracellular matrix turnover in the trabecular meshwork.
bioRxiv · Jan 25, 2025 · PreprintImmunology