Author

Violet Bupp-Chickering

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Genomics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Revathi BalasubramanianiD· 4 shared Simon W. M. JohniD· 4 shared Christa L. MontgomeryiD· 3 shared Jiang X. QianiD· 3 shared John PeregriniD· 3 shared Marina SimóniD· 3 shared Nicholas G. TolmaniD· 3 shared Ruth A. KellyiD· 3 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Revathi BalasubramanianORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

Nicholas G. Tolman, Taibo Li, Revathi Balasubramanian, Guorong Li, Rebecca Pfeiffer, Violet Bupp-Chickering, Ruth A. Kelly, Marina Simón, John Peregrin, Christa L. Montgomery, Bryan Jones, William Daniel Stamer, Jiang X. Qian, Simon W. M. John

The paper identifies mitochondrial dysfunction in a glaucoma model using single-cell analysis and shows that vitamin B3 treatment protects against IOP elevation.

eLife · Jan 20, 2026Peer-reviewedMolecular Biology

Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal

Revathi Balasubramanian, Nicholas G. Tolman, Taibo Li, Abdul Hannan, Violet Bupp-Chickering, Karina Polanco, Aakriti Bhandari, Sally Zhou, Marina Simón, John Peregrin, Christa L. Montgomery, Krishnakumar Kizhatil, Jiang X. Qian, Simon W. M. John

The paper uses single-cell transcriptomics to characterize anterior segment development, identifying cell types, pathways, and signaling networks in trabecular meshwork and Schlemm's canal formation.

bioRxiv · Aug 15, 2025 · PreprintDevelopmental Biology

Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis

Katy C. Liu, Aleksander O. Grimsrud, María Fernanda Suárez, Darren M. Schuman, Michael Lucio De Ieso, Megan N. Kuhn, Ruth A. Kelly, Rose Mathew, Joan Kalnitsky, Matthias Mack, Florent Ginhoux, Violet Bupp-Chickering, Revathi Balasubramanian, Simon W. M. John, William Daniel Stamer, Daniel R. Saban

The paper identifies resident tissue macrophages as critical for maintaining intraocular pressure homeostasis by regulating extracellular matrix turnover in the trabecular meshwork.

bioRxiv · Jan 25, 2025 · PreprintImmunology

Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states

Revathi Balasubramanian, Krishnakumar Kizhatil, Taibo Li, Nicholas G. Tolman, Aakriti Bhandari, Graham Clark, Violet Bupp-Chickering, Ruth A. Kelly, Sally Zhou, John Peregrin, Marina Simón, Christa L. Montgomery, William Daniel Stamer, Jiang X. Qian, Simon W. M. John

The paper performs transcriptomic analyses of Schlemm's canal endothelial cells to reveal their lymphatic identity, three major cell states, and interactions with trabecular meshwork cells.

eLife · Oct 18, 2024Peer-reviewedGenomics