Author

Maya O. Tree

Central Michigan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Organism:zebrafish· 1

Frequent Co-Authors

Emmanuel L. CrespoiD· 5 shared Ute HochgeschwenderiD· 5 shared Christopher I. MooreiD· 4 shared Diane LipscombeiD· 4 shared Nathan C. ShaneriD· 4 shared Alexander D. Silvagnoli· 3 shared Ashley N. SlavieroiD· 3 shared Gerard G. LambertiD· 3 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersNeuroscience

Emmanuel L. CrespoORCID

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Author profile →

5 papers

Recent·Most cited

Control of Synaptic Communication through Molecularly Engineered Bioluminescence Light Emission and Sensing

Ashley N. Slaviero, Mansi Prakash, Rachel Schumaker, Emmanuel L. Crespo, Alexander D. Silvagnoli, Maya O. Tree, Gerard G. Lambert, Christopher I. Moore, Nathan C. Shaner, Diane Lipscombe, Ute Hochgeschwender

This paper introduces a modular platform called Interluminescence that uses bioluminescent light to control synaptic transmission by activating optogenetic ion channels in postsynaptic neurons.

Communications Biology · Jul 10, 2026Peer-reviewedNeuroscience

A Bioluminescent Activity Dependent Platform, BLADe, for Converting Intracellular Activity to Photoreceptor Activation

Emmanuel L. Crespo, Akash Pal, Mansi Prakash, Alexander D. Silvagnoli, Zohair Zaidi, Manuel Gomez‐Ramirez, Maya O. Tree, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender

The paper introduces BLADe, a platform that converts intracellular activity into photoreceptor activation using bioluminescent sensors and actuators, demonstrating its use in neurons for activity-dependent gene expression and neural dynamics control.

Scientific Reports · May 11, 2026Peer-reviewedNeuroscience

CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

Gerard G. Lambert, Emmanuel L. Crespo, Jeremy Murphy, Kevin L. Turner, Emily Gershowitz, Michaela Cunningham, Daniela Boassa, Selena Luong, Dmitrijs Celinskis, Justine J. Allen, Stephanie Venn, Yunlu Zhu, Mürsel Karadas, Jiakun Chen, Roberta Marisca, , Nathan C. Shaner

This paper introduces CaBLAM, a bioluminescent Ca2+ indicator with improved dynamic range and Ca2+ affinity, enabling high-resolution imaging of cellular activity in cultured neurons and in vivo.

Nature Methods · Dec 2, 2025Peer-reviewedNeuroscience

Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington's Disease Pathogenesis

Ebenezer C Ikefuama, Ashley N. Slaviero, Alexander D. Silvagnoli, Emmanuel L. Crespo, Raegan Schalau, Madison L Gott, Maya O. Tree, Gary Leo Dunbar, Julien Rossignol, Ute Hochgeschwender

The paper investigates presymptomatic manipulation of cortical neuron activity in HD mice to restore E/I balance and slow disease progression.

iScience · Feb 13, 2025Peer-reviewedNeuroscience

Engineering luminopsins with improved coupling efficiencies

Ashley N. Slaviero, Nipun Gorantla, Jacob Simkins, Emmanuel L. Crespo, Ebenezer C Ikefuama, Maya O. Tree, Mansi Prakash, Andreas Björefeldt, Lauren M. Barnett, Gerard G. Lambert, Diane Lipscombe, Christopher I. Moore, Nathan C. Shaner, Ute Hochgeschwender

This study evaluates factors affecting luminopsin efficacy and identifies strategies to improve their function through molecular evolution.

Neurophotonics · Mar 29, 2024Peer-reviewedMolecular Biology