NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in mice
Ruolin Zhang, Weibing Mao, Lumeng Niu, Wendai Bao, Yiqi Wang, Ying Wang, Yasha Zhu, Zhihao Yang, Jincao Chen, Jiawen Dong, Meng Cai, Zilong Yuan, Haikun Song, Guangqiang Li, Min Zhang, , Zhiqiang Dong
This study shows that NSC-derived exosomes improve the therapeutic effects of NSC transplantation in mice with cerebral ischemia by reducing inflammation, oxidative stress, and promoting differentiation and tissue recovery.
eLife · Apr 4, 2023Peer-reviewedNeuroscience