Author

Mi Chen

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

Diane S. KrauseiD· 2 shared Ailin Han· 1 shared Amin H. NassariD· 1 shared Andreas P. Pintado-UrbanciD· 1 shared Chia‐Yi LeeiD· 1 shared Christian RamireziD· 1 shared Esen SefikiD· 1 shared Fengrui ZhangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Diane S. KrauseORCID

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2 papers

Recent·Most cited

Reverse genetics in humanized mice reveals CARD8-mediated pyroptosis causing pancytopenia in human DPP9 deficiency

Tianli Xiao, J. Richard Brewer, Maximillian J. Carlino, Ailin Han, Yamato J. Takabe, Chia‐Yi Lee, Fengrui Zhang, Mi Chen, Holly N. Blackburn, Amin H. Nassar, Qiankun Wang, Kristen Brennand, Liang Shan, Esen Sefik, Diane S. Krause, Richard Anthony Flavell

This study uses reverse genetics in humanized mice to show that DPP9 deficiency causes CARD8-mediated pyroptosis in human hematopoietic stem and progenitor cells, leading to pancytopenia.

Journal of Clinical Investigation · Sep 14, 2026Peer-reviewedImmunology

RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and WNT pathway activation

Madeline Y. Mayday, Giulia Biancon, Manyi Wei, Christian Ramirez, Irene Moratti, Andreas P. Pintado-Urbanc, Jether Amos Espinosa, Mi Chen, Lin Wang, Matthew D. Simon, Yaara Ofir-Rosenfeld, Oliver Rausch, Toma Tebaldi, Stephanie Halene, Diane S. Krause

This study shows that the RBM15-MKL1 fusion protein drives leukemia through m6A methylation and WNT pathway activation, with METTL3 inhibition reducing tumor growth.

Blood · May 28, 2025Peer-reviewedCancer Biology