Author

Michael Chan

Public Health Agency of Canada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

Guodong LiuiD· 2 shared Jordan WightiD· 2 shared Kevin Tierney· 2 shared Kimberly Azaransky· 2 shared Kirby I. Cronin· 2 shared Logan BanadygaiD· 2 shared Natalie A. PrystajeckyiD· 2 shared Patrick K.C. TangiD· 2 shared

Activity by Year

2017-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

Guodong LiuORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

rVSV-EBOV vaccination protects ferrets from lethal Bundibugyo virus disease

Jordan Wight, Guodong Liu, Michael Chan, Sarah J. Medina, David Lu, Wenguang Cao, Samantha J. Krosta, Kevin Tierney, Kimberly Azaransky, Logan Banadyga

This study shows that the rVSV-EBOV vaccine protects ferrets from lethal BDBV infection, suggesting its potential use in mitigating the ongoing outbreak.

bioRxiv · Aug 26, 2026 · PreprintMicrobiology

Characterization of Atypical Ebola Virus Disease in Ferrets

Wenguang Cao, Shihua He, Helene Schulz, Jordan Wight, Michael Chan, Karla Emeterio, Guodong Liu, Jonathan Audet, Kevin Tierney, Kimberly Azaransky, Kathy Frost, Lilianne Gee, Peter McQueen, Patrick Chong, Sarah B. Sulkosky, , Logan Banadyga

This study describes atypical Ebola virus disease in ferrets treated with a monoclonal antibody cocktail, showing delayed disease recrudescence with neurological involvement and brain inflammation.

PLoS Pathogens · May 4, 2026Peer-reviewedMicrobiology

Maternal Obesity Decreases Offspring Lifespan

Eric Moore, Ramasamy Selvarani, Kavitha Kurup, Michael Chan, M. Saminathan, N. Pazhanivel, Kai Ding, Alexandra L Ford, Brianne M Taylor, Karen R. Jonscher, Arlan G Richardson, Jacob E. Friedman, Archana Unnikrishnan

This study shows maternal obesity reduces offspring lifespan in mice, linked to early developmental fibrotic changes across multiple organs.

Molecular Metabolism · Feb 11, 2026Peer-reviewedPhysiology

Spatiotemporal dynamics of river viruses, bacteria and microeukaryotes

Thea Van Rossum, Miguel I. Uyaguari-Diaz, Marli Vlok, Michael A. Peabody, Alvin Tian, Kirby I. Cronin, Michael Chan, Matthew A. Croxen, William W.L. Hsiao, Judith Isaac-Renton, Patrick K.C. Tang, Natalie A. Prystajecky, Curtis A. Suttle, Fiona S.L. Brinkman

This study examines the spatiotemporal dynamics of riverine microbial communities, including viruses, bacteria, and microeukaryotes, revealing distinct patterns and highlighting the need for holistic analysis.

bioRxiv · Feb 5, 2018 · PreprintMicrobiology

Antibiotic resistance genes in agriculture and urban influenced watersheds in southwestern British Columbia

Miguel I. Uyaguari-Díaz, Matthew A. Croxen, Zhiyao Luo, Kirby I. Cronin, Michael Chan, Waren N. Baticados, Matthew J. Nesbitt, Shaorong Li, Kristi Miller, Damion Dooley, William Hsiao, Judith L. Isaac-Renton, Patrick Tang, Natalie Prystajecky

This study identifies antibiotic resistance genes in agricultural and urban watersheds using metagenomics and qPCR, finding higher ARG abundance in impacted sites.

bioRxiv · Feb 1, 2017 · PreprintMicrobiology