Hydrodynamic shear enables enrichment of functional tumor antigen-reactive T cells
Prem Santhosh Subramanian, Michelle Fu, Layla C Semaan, Asfa Sultana Sher, Bhupinder S. Shergill, Steven C. George, Venktesh S. Shirure
This paper introduces a microfluidic platform using hydrodynamic shear to enrich antigen-specific T cells, achieving 35-fold enrichment from peripheral blood mononuclear cells.
bioRxiv · Jul 8, 2026 · PreprintBioengineering