Crystal structure of the MBD domain of MBD3 in complex with methylated CG DNA
Ke Liu, Ming Lei, Bing Gan, Harry Cheng, Yanjun Li, Jinrong Min
This study determines the crystal structure of the MBD3 MBD domain bound to methylated CG DNA, revealing its binding mechanism and preference for mCG over hmCG.
bioRxiv · Jun 11, 2018 · PreprintBiochemistry