Multicopper oxidase mediated single-carbon insertion for skeletal remodeling
Bo Jiang, Binbin Chen, Hongxun Gao, Jiaxin Huang, Xiao Liu, Mingjie Ma, Yajie Alison Wang
This paper introduces a multicopper oxidase-catalyzed method for single-carbon insertion in skeletal editing, enabling the synthesis of bioactive compounds with improved antibacterial activity.
bioRxiv · Mar 31, 2026 · PreprintBioengineering