Shared Maturation Pathways of HIV-1 Envelope-reactive V3-glycan bnAb Lineages in Human and Rhesus Macaque
Matthew Clark, Hui Li, Mitchell Martin, Tyler D. Evangelous, S. Gobeil, Madison Berry, Kshitij Wagh, Elena E. Giorgi, Michael P. Hogarty, Chengyan Zhao, Shuyi Wang, Lorie Marchitto, Wenge Ding, Younghoon Park, Juliette M. Rando, , Wilton B. Williams
The paper identifies shared maturation pathways of V3-glycan broadly neutralizing antibody lineages in humans and rhesus macaques, revealing convergent mutations and evolution patterns.
bioRxiv · Jan 30, 2026 · PreprintImmunology