M5 positive allosteric modulation alleviates parkinsonian motor deficits
Nicole Chambers, Dominic Hall, Morgan Kaplan, Sarah Garan, Tyler Eichner, Mark S. Moehle
This study investigates the potential of M5 positive allosteric modulators to alleviate parkinsonian motor deficits without causing dyskinesia or impairing L-DOPA efficacy.
bioRxiv · Aug 21, 2025 · PreprintNeuroscience