Conditional Knockout of Striatal Gnal Produces Dystonia-like Motor Phenotypes
Nicole Chambers, Dominic Hall, Stephanie Barsoum, Evan Miller, Tiffany Curry, Morgan Kaplan, Sarah Garan, Ignacio Gallardo, Rick Staab, Douglas Nabert, Kevin Hutchinson, Michael Millett, Mark S. Moehle
Knocking out Gnal in the striatum of mice leads to dystonia-like motor symptoms and increased excitability in striatal spiny projection neurons.
bioRxiv · Aug 26, 2024 · PreprintNeuroscience