Author

Morgan Sedorovitz

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Organism:non-human primate· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Leah C. ByrneiD· 2 shared William R. StaufferiD· 2 shared Andreas R. PfenningiD· 1 shared Andreea C. BostaniD· 1 shared Ashley R. BrowniD· 1 shared Aydin AlikayaiD· 1 shared BaDoi N. PhaniD· 1 shared Bilge Esin ÖztürkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Leah C. ByrneORCID

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Author profile →

2 papers

Recent·Most cited

Structural dynamics insights into principles underlying the fitness of new broadly potent AAVs

Molly E. Johnson, Bilge Esin Öztürk, Thomas H. Tugwell, Maryl Lambros, Haley N. Janowitz, Keevon Flohr, Morgan Sedorovitz, Laura Campello, J Hartung, Brett C. Hogle, Megan E. Gillespie, Hannah Schriever, Hamzah Aweidah, Janis Koester, Inga Clausen, , Leah C. Byrne

The paper develops a new AAV engineering workflow, scAAVengr-Hunt, to create potent vectors and identifies a structural mechanism underlying their broad species and tissue potency.

bioRxiv · May 17, 2026 · PreprintBioengineering

Cell Type Specific Enhancers for Dorsolateral Prefrontal Cortex.

Jing He, BaDoi N. Phan, Willa G. Kerkhoff, Aydin Alikaya, Tao Hong, Olivia R Brull, J. Megan Fredericks, Morgan Sedorovitz, Chaitanya Srinivasan, Michael J. Leone, Olivia M. Wirfel, Ashley R. Brown, Samuel Dauby, Rachel K. Tittle, Meng Kuan Lin, , William R. Stauffer

The paper identifies cell type-specific enhancers for the DLPFC in NHPs using single nucleus RNA-Seq and ATAC-Seq, validates them with AAV injections, and demonstrates functional expression in specific neuron types.

Neuron · May 1, 2025Peer-reviewedNeuroscience