Identification of NPC1 as a novel SARS-CoV-2 intracellular target
I. Garcia-Dorival, M. A. Cuesta-Geijo, L. Barrado-Gil, I. Galindo, J. Urquiza, A. Del Puerto, C. Gil, N. Campillo, A. Martinez, C. Alonso
The paper identifies NPC1 as a novel SARS-CoV-2 intracellular target, showing its interaction with the viral nucleoprotein and its inhibition by small molecules that also block EBOV entry.
bioRxiv · Dec 19, 2020 · PreprintMicrobiology