Palmitate-induced toxicity is associated with impaired mitochondrial respiration and accelerated oxidative stress in cultured cardiomyocytes: the critical role of Coenzyme Q9/10
P. V. Dludla, S. Silvestri, P. Orlando, S. Mazibuko-Mbeje, R. Johnson, F. Marcheggiani, I. Cirilli, C. J. F. Muller, J. Louw, N. Chellan, N. Obonye, B. B. Nkambule, L. Tiano
This study investigates how palmitate affects mitochondrial respiration, oxidative stress, and CoQ levels in cardiomyocytes, showing that CoQ response is critical for mitochondrial protection.
bioRxiv · Nov 4, 2019Biochemistry