Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
F. Zhao, Z. T. Berndsen, N. Pedreno-Lopez, A. Burns, J. D. Allen, S. Barman, W.-H. Lee, S. Chakraborty, S. Gnanakaran, L. M. Sewall, G. Ozorowski, O. Limbo, G. Song, P. Yong, S. Callaghan, , D. Sok
This study identifies nAbs against SIVmac239, reveals structural features of its Env trimer, and shows passive transfer of nAbs protects macaques from infection.
bioRxiv · Dec 22, 2021Immunology