Tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds
S. Wurster, A. M. Tatara, N. D. Albert, A. S. Ibrahim, J. Heitman, S. C. Lee, A. C. Shetty, C. McCracken, K. T. Graf, A. G. Mikos, V. M. Bruno, D. P. Kontoyiannis
This study shows that tornadic shear stress induces a transient, calcineurin-dependent hyper-virulent phenotype in Mucorales molds, with potential therapeutic implications for trauma-related mucormycosis.
bioRxiv · Feb 14, 2020Microbiology