Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung
H. Liu, W. Xu, V. M. Bruno, Q. T. Phan, N. V. Solis, C. A. Woolford, R. Ehrlich, A. C. Shetty, C. McCracken, J. Lin, A. P. Mitchell, S. G. Filler
The paper identifies two transcription factors, RlmA and Ace1, critical for Aspergillus fumigatus virulence by analyzing gene expression during lung infection in mice.
bioRxiv · Dec 23, 2020Microbiology