Author

N. Dinesh Kumar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. M. ter Ellen· 2 shared B. Troost· 2 shared D. P. I. van de Pol· 2 shared D. van Gosliga· 2 shared E. M. Bouma· 2 shared H. H. van der Ende-Metselaar· 2 shared I. A. Rodenhuis-Zybert· 2 shared J. M. Smit· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. M. ter Ellen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BNIP3 regulates Chikungunya virus infection independently of autophagy and cell death

L. Echavarria-Consuegra, n. dinesh kumar, M. Mauthe, d. van de pol, F. Reggiori, J. M. Smit

This study identifies BNIP3 as an antiviral factor that inhibits Chikungunya virus infection independently of autophagy and cell death, acting during the early stages of the viral cycle.

bioRxiv · Aug 22, 2022 · PreprintMicrobiology

N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase

J. Rosenau, I. L. Grothaus, Y. Yang, N. Dinesh Kumar, L. C. Ciacchi, S. Kelm, M. Waespy

This study shows that N-glycans on Trypanosoma congolense trans-sialidase affect substrate affinity but not conversion rate, with molecular dynamics revealing structural interactions that enhance enzyme function.

bioRxiv · Dec 13, 2021Biochemistry

Cooperativity of catalytic and lectin-like domain of T. congolense trans-sialidase modulates its catalytic activity

M. Waespy, T. T. Gbem, N. Dinesh Kumar, S. Solaiyappan Mani, J. Rosenau, F. Dietz, S. Kelm

This study shows that the lectin domain of T. congolense trans-sialidase modulates its catalytic activity by favoring trans-sialylation over hydrolysis when interacting with specific carbohydrates.

bioRxiv · May 28, 2021Biochemistry

Moxidectin and ivermectin inhibit SARS-CoV-2 replication in Vero E6 cells but not in human primary airway epithelium cells

N. Dinesh Kumar, B. M. ter Ellen, E. M. Bouma, B. Troost, D. P. I. van de Pol, H. H. van der Ende-Metselaar, D. van Gosliga, L. Apperloo, O. A. Carpaij, M. van den Berge, M. C. Nawijn, Y. Stienstra, I. A. Rodenhuis-Zybert, J. Smit

This study compares the antiviral activity of moxidectin and ivermectin against SARS-CoV-2 in Vero E6 cells and human airway epithelial cells, finding inhibition in Vero cells but not in human cells.

bioRxiv · May 17, 2021Microbiology

Resveratrol And Pterostilbene Potently Inhibit SARS-CoV-2 Replication In Vitro

B. M. ter Ellen, N. Dinesh Kumar, E. M. Bouma, B. Troost, D. P. I. van de Pol, H. H. van der Ende-Metselaar, L. Apperloo, D. van Gosliga, M. van den Berge, M. C. Nawijn, P. H. J. van der Voort, J. Moser, I. A. Rodenhuis-Zybert, J. M. Smit

This study shows resveratrol and pterostilbene inhibit SARS-CoV-2 replication in vitro in multiple cell types, with long-lasting antiviral effects.

bioRxiv · Sep 24, 2020 · PreprintMicrobiology