J. Rosenau

This study shows that N-glycans on Trypanosoma congolense trans-sialidase affect substrate affinity but not conversion rate, with molecular dynamics revealing structural interactions that enhance enzyme function.

This study investigates trypanosome prevalence and vector density in two Ghanaian districts, finding high infection rates in tsetse flies and pigs with T. congolense as the dominant species.

This study shows that the lectin domain of T. congolense trans-sialidase modulates its catalytic activity by favoring trans-sialylation over hydrolysis when interacting with specific carbohydrates.