Author

N. Duarte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Penha-Goncalves· 3 shared I. Coelho· 2 shared M. P. Macedo· 2 shared A. Barros· 1 shared B. Costa-Silva· 1 shared C. Chhatbar· 1 shared H. Ali· 1 shared J. M. d. Silva· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

C. Penha-Goncalves

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivFeb 14, 2022

Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response.

T. F. Pais, H. Ali, J. M. d. Silva…·C. Penha-Goncalves

This paper identifies STING1 activation by heme from Plasmodium-infected erythrocytes as a key driver of cerebral malaria through type I IFN and CXCL10-mediated inflammation.

DOI 10.1073/pnas.2206327119

mouseexperimental assay

MicrobiologybioRxivPreprintNov 28, 2019

Trem-2 modulation of gut microbiota is blunted during hepatotoxic injury and uncoupled from liver repair responses

I. Coelho, N. Duarte, M. P. Macedo, C. Penha-Goncalves

This study shows that Trem-2 modulates gut microbiota composition but this effect is uncoupled from its protective role in liver repair during hepatotoxic injury.

DOI 10.1101/857078

mousebulk RNA-seq

ImmunologybioRxivOct 30, 2019

Trem-2 promotes emergence of restorative macrophages and endothelial cells during recovery from hepatic tissue damage.

I. Coelho, N. Duarte, A. Barros…·C. Penha-Goncalves

This study shows Trem-2 promotes the transition of liver macrophages to restorative phenotypes and influences endothelial cell de-differentiation during liver recovery from injury.

DOI 10.3389/fimmu.2020.616044

mousebulk RNA-seq