Ankylosis homologue mediates cellular efflux of ATP, not pyrophosphate
F. Szeri, F. Niaziorimi, S. Donnelly, N. Fariha, M. Tertyshnaia, D. Patel, S. Lundkvist, K. van de Wetering
The paper shows ANKH mediates ATP release, not PPi, and both ANKH and ABCC6 contribute to plasma PPi by extruding NTPs, not PPi directly.
bioRxiv · Aug 27, 2021Biochemistry