Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C
A. S. Baier, N. Gioacchini, P. Eek, E. M. Leith, S. Tan, C. L. Peterson
This study shows that SWR1C requires both nucleosomal acidic patches for H2A.Z deposition, revealing a 'pincer-like' engagement mechanism and a conserved arginine-rich motif in Swc5.
bioRxiv · Dec 8, 2021Biochemistry