Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome depleted regions
B. T. Donovan, H. Chen, P. Eek, Z. Meng, C. Jipa, S. Tan, L. Bai, M. G. Poirier
This study shows how Cbf1's HLH region interacts with histones to slow nucleosome dissociation, enabling chromatin opening.
bioRxiv · Mar 17, 2022Biophysics