Author

N. Gobeau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kuemmel· 1 shared A. Walz· 1 shared C. Demarta-Gatsi· 1 shared C. Gumpp· 1 shared D. J. Price· 1 shared J. A. Simpson· 1 shared J. J. Moehrle· 1 shared J. J. Möhrle· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Kuemmel

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A new in vitro checkerboard-parasite reduction ratio interaction assay for early de-risk of clinical development of antimalarial combinations

C. Demarta-Gatsi, S. Wicha, A. Walz, M. H. Cherkaoui-Rbati, C. Gumpp, N. Gobeau, J. J. Möhrle, M. Rottmann

This paper introduces an in vitro assay to predict antimalarial drug combination efficacy, showing it can accurately predict clinical trial outcomes and provide detailed pharmacodynamic insights.

bioRxiv · Apr 19, 2022 · PreprintMicrobiology

Seeking an optimal dosing regimen for OZ439-DSM265 combination therapy for treating uncomplicated falciparum malaria

S. Dini, S. G. Zaloumis, D. J. Price, N. Gobeau, A. Kuemmel, M. Cherkaoui, J. J. Moehrle, J. S. McCarthy, J. A. Simpson

This study uses a mathematical model to determine an optimal dosing regimen for OZ439-DSM265 combination therapy to treat uncomplicated falciparum malaria, predicting a regimen that cures 90% of patients within 42 days.

bioRxiv · Nov 2, 2020Pharmacology & Toxicology