Author

M. Rottmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Burrell· 1 shared A. Pfenniger· 1 shared A. Walz· 1 shared A.-M. Zeeman· 1 shared B. M. Shanab· 1 shared B. P. Knight· 1 shared C. Demarta-Gatsi· 1 shared C. Gumpp· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

A. Burrell

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Author profile →

3 papers

Recent·Most cited

A new in vitro checkerboard-parasite reduction ratio interaction assay for early de-risk of clinical development of antimalarial combinations

C. Demarta-Gatsi, S. Wicha, A. Walz, M. H. Cherkaoui-Rbati, C. Gumpp, N. Gobeau, J. J. Möhrle, M. Rottmann

This paper introduces an in vitro assay to predict antimalarial drug combination efficacy, showing it can accurately predict clinical trial outcomes and provide detailed pharmacodynamic insights.

bioRxiv · Apr 19, 2022 · PreprintMicrobiology

Persistence of Plasmodium cynomolgi hypnozoites in cynomolgus monkey iPS-derived hepatocytes

M. Pellisson, A.-M. Zeeman, T. Doll, L. Kirchhofer-Allan, S. Schuierer, G. Roma, E. L. Flannery, S. A. Mikolajczak, C. H. M. Kocken, P. Maeser, M. Rottmann, M. Mueller

This study develops an in vitro model using cynomolgus monkey iPS-derived hepatocytes to study Plasmodium cynomolgi hypnozoite formation and liver stage dormancy, aiding drug discovery.

bioRxiv · Nov 16, 2021 · PreprintCell Biology

Regions of Highly Recurrent Electrogram Morphology at Sites of Low Cycle Length Accurately Reflect Arrhythmogenic Substrate for Atrial Fibrillation - Implications For a New, Mechanism Guided Therapeutic Approach for Atrial Fibrillation

S. Yoo, M. Rottmann, J. Ng, D. A. Johnson, B. M. Shanab, A. Pfenniger, G. E. Geist, S. Mandava, A. Burrell, W. Zhang, J. A. Wasserstrom, B. P. Knight, R. Passman, J. Goldberger, R. Arora

This study identifies electrogram morphology recurrence as a marker of arrhythmogenic substrate in atrial fibrillation, suggesting it could guide targeted ablation therapy.

bioRxiv · Dec 10, 2020 · PreprintPhysiology