MicrobiologybioRxivPreprint
A new in vitro checkerboard-parasite reduction ratio interaction assay for early de-risk of clinical development of antimalarial combinations
C. Demarta-Gatsi, S. Wicha, A. Walz…·M. Rottmann
This paper introduces an in vitro assay to predict antimalarial drug combination efficacy, showing it can accurately predict clinical trial outcomes and provide detailed pharmacodynamic insights.
DOI 10.1101/2022.04.19.488858