Author

N. Jakimo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. M. Jacobson· 3 shared P. Chatterjee· 3 shared L. Nip· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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3 shared papersBioengineering

J. M. Jacobson

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3 papers

Recent·Most cited

Robust Genome Editing of Single-Base PAM Targets with Engineered ScCas9 Variants

P. Chatterjee, N. Jakimo, J. M. Jacobson

This study engineers ScCas9 variants to enable robust genome editing at single-base PAM targets with improved activity and fidelity.

bioRxiv · Apr 26, 2019 · PreprintBioengineering

A Cas9 with Complete PAM Recognition for Adenine Dinucleotides

N. Jakimo, P. Chatterjee, L. Nip, J. M. Jacobson

This paper identifies a Cas9 variant with expanded PAM recognition for adenine dinucleotides, enabling broader gene editing capabilities in human cells.

bioRxiv · Sep 27, 2018Bioengineering

Divergent PAM Specificity of a Highly-Similar SpCas9 Ortholog

P. Chatterjee, N. Jakimo, J. M. Jacobson

This study characterizes the PAM specificity of ScCas9, a Cas9 ortholog from Streptococcus canis, showing divergent PAM affinity and developing a bioinformatics pipeline to explore microbial PAM diversity.

bioRxiv · Feb 2, 2018Microbiology