Inhibition of Neisseria gonorrhoeae complement-mediated killing during acute gonorrhoea is dependent upon the IgG2:IgG3 antibody ratio
S. A. McKeand, S. E. Faustini, A. Cook, N. Kennett, M. T. Drayson, A. F. Cunningham, I. R. Henderson, J. D. C. Ross, J. A. Cole, A. E. Rossiter-Pearson
The paper identifies that a high IgG2:IgG3 antibody ratio inhibits complement-mediated killing of Neisseria gonorrhoeae, revealing a mechanism for bacterial resistance.
bioRxiv · Sep 26, 2023 · PreprintMicrobiology