The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling
L. Pelz, L. Dossou, N. Kompier, R. Juttner, G. Siemonsmeier, N. Meyer, E. D. Lowenstein, I. Lahmann, H. Kettenmann, C. Birchmeier, F. G. Rathjen
This study shows that BT-IgSF is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling, with knockout leading to increased connexin43 clustering and reduced coupling.
bioRxiv · Jun 17, 2022 · PreprintCell Biology