N. Meyer

CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival

This study shows that inhibiting CDK12 and CDK13 reduces glioma cell proliferation and migration, and disrupts transcription and cell cycle progression in glioblastoma.

Spatio-temporal dynamics of the proton motive force on single bacterial cells

This study investigates the spatio-temporal dynamics of the proton motive force (PMF) in single bacterial cells using light-activated proton pumps and flagellar motors, revealing rapid homogenization and fast temporal changes.

The IgCAM BT-IgSF (IgSF11) is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling

This study shows that BT-IgSF is essential for connexin43-mediated astrocyte-astrocyte and ependymal cell-cell coupling, with knockout leading to increased connexin43 clustering and reduced coupling.

Pronounced uptake and metabolism of organic substrates by diatoms revealed by pulse-labeling metabolomics

This study shows diatoms efficiently take up and transform organic substrates from competitors, revealing their significant role in oceanic organic material cycling.

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

This study shows that pimozide and loperamide induce glioma cell death through autophagy, lipotoxicity, and lysosomal membrane permeabilization in MZ-54 GBM cells.