Prolonged lag time results in small colony variants and reflects a sub-population of persisters in vivo
C. Vulin, N. Leimer, M. Huemer, M. Ackermann, A. S. Zinkernagel
The paper shows that small colony variants in Staphylococcus aureus result from prolonged lag times, not mutations, and are linked to antibiotic tolerance and persisters in vivo.
bioRxiv · Mar 12, 2018Microbiology