Carcinoma-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment
E. D. Wrenn, A. A. Apfelbaum, E. R. Rudzinski, X. Deng, W. Jiang, S. Sud, R. A. Van Noord, E. A. Newman, N. M. Garcia, V. J. Hoglund, S. S. Bhise, S. B. Kanaan, O. G. Waltner, S. N. Furlan, E. R. Lawlor
This study identifies a subpopulation of Ewing sarcoma cells with CAF-like properties that remodel the tumor microenvironment through ECM deposition.
bioRxiv · Apr 12, 2023 · PreprintCancer Biology