LPS induces GFAT2 expression to promote O-GlcNAcylation and attenuate inflammation in macrophages
H. Al-Mukh, L. Baudoin, A. Bouaboud, J.-L. Sanchez-Salgado, N. Maraqa, M. Khair, P. Pagesy, G. Bismuth, F. Niedergang, T. Issad
This study shows LPS increases GFAT2 expression in macrophages, enhancing O-GlcNAcylation and reducing inflammation.
bioRxiv · Mar 22, 2020Biochemistry