Author

T. Issad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bouaboud· 2 shared P. Pagesy· 2 shared C. G. Myers· 1 shared C. W. Fishwick· 1 shared D. J. Beech· 1 shared E. M. Clavane· 1 shared F. Niedergang· 1 shared G. Bismuth· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

A. Bouaboud

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells

C. G. Myers, H. Viswambharan, N. Haywood, K. Bridge, S. J. Turvey, T. Armstrong, L. Lunn, P. J. Meakin, E. M. Clavane, D. J. Beech, R. M. Cubbon, S. B. Wheatcroft, M. J. McPhillie, T. Issad, C. W. Fishwick, , K. J. Simmons

This paper identifies a small molecule that reduces IR:IGF-1R hybrid formation in human endothelial cells, increasing Akt phosphorylation and altering PI3-kinase signaling.

bioRxiv · Mar 11, 2024Cell Biology

Short OGA is targeted to the mitochondria and regulates mitochondrial reactive oxygen species level

P. Pagesy, A. Bouaboud, Z. Feng, P. Hulin, T. Issad

This study identifies short-OGA as a mitochondrial enzyme that reduces O-GlcNAcylation and increases mitochondrial reactive oxygen species levels.

bioRxiv · Dec 25, 2021 · PreprintCell Biology

LPS induces GFAT2 expression to promote O-GlcNAcylation and attenuate inflammation in macrophages

H. Al-Mukh, L. Baudoin, A. Bouaboud, J.-L. Sanchez-Salgado, N. Maraqa, M. Khair, P. Pagesy, G. Bismuth, F. Niedergang, T. Issad

This study shows LPS increases GFAT2 expression in macrophages, enhancing O-GlcNAcylation and reducing inflammation.

bioRxiv · Mar 22, 2020Biochemistry