Salmonella Typhimurium induces NAIP/NLRC4- and NLRP3/ASC-independent, caspase-1/4-dependent inflammasome activation in human intestinal epithelial cells
N. Naseer, R. Bauer, J. Zhang, I. E. Brodsky, I. Rauch, S. Shin
This study shows that human intestinal epithelial cells use caspase-1/4-dependent inflammasomes, not NAIP/NLRC4 or NLRP3/ASC, to respond to Salmonella Typhimurium.
bioRxiv · Dec 9, 2021 · PreprintMicrobiology