Cell-free chromatin particles from dying cells promote the induction of an immune response in human lymphocytes
S. Shabrish, G. V. Raghuram, N. Raphael, R. Narayanan, R. Lopes, D. Kondhalkar, N. K. Khare, I. Mittra
The paper shows that cell-free chromatin particles from dying cells trigger immune responses in human lymphocytes via the cGAS-STING pathway.
bioRxiv · Aug 7, 2023 · PreprintImmunology