Author

N. Sim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Y. Li· 2 shared B. K. T. Tan· 1 shared J.-M. Carter· 1 shared K. Deka· 1 shared S.-M. Tan· 1 shared Y. Sim· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

Y. Li

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in Triple-Negative Breast Cancer

N. Sim, J.-M. Carter, K. Deka, B. K. T. Tan, Y. Sim, S.-M. Tan, Y. Li

This study shows that TWEAK/Fn14 signalling rewires the transcriptomic and epigenomic landscape of TNBC, promoting metastasis through super-enhancer-driven metabolic reprogramming.

bioRxiv · May 15, 2024 · PreprintCancer Biology

NF-κB/p52 augments ETS1 binding genome-wide to promote glioma progression

N. Sim, Y. Li

This study shows that non-canonical NF-κB activation enhances p52 binding to the ETS1 promoter, leading to ETS1 overexpression and transcriptional activation of glioma-promoting genes.

bioRxiv · Jan 11, 2023 · PreprintCancer Biology