Author

Y. Sim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. K. T. Tan· 1 shared J.-M. Carter· 1 shared K. Deka· 1 shared N. Sim· 1 shared S.-M. Tan· 1 shared Y. Li· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

B. K. T. Tan

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1 paper

Recent·Most cited

TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in Triple-Negative Breast Cancer

N. Sim, J.-M. Carter, K. Deka, B. K. T. Tan, Y. Sim, S.-M. Tan, Y. Li

This study shows that TWEAK/Fn14 signalling rewires the transcriptomic and epigenomic landscape of TNBC, promoting metastasis through super-enhancer-driven metabolic reprogramming.

bioRxiv · May 15, 2024 · PreprintCancer Biology