Efficient inhibition of SARS-CoV-2 strains by a novel ACE2-IgG4-Fc fusion protein with a stabilized hinge region
H. L. Svilenov, J. Sacherl, A. Reiter, L. Wolff, C.-C. Chen, M. Stern, F.-P. Wachs, N. Simonavicius, S. Pippig, F. Wolschin, J. Buchner, C. Brockmeyer, U. Protzer
This paper describes a novel ACE2-IgG4-Fc fusion protein that inhibits SARS-CoV-2 strains efficiently with improved pharmaceutical properties and broad antiviral activity.
bioRxiv · Dec 6, 2020 · PreprintImmunology