The Sequence Basis for Selectivity of Ephrin-B2 Ligand for Eph Receptors and Pathogenic Henipavirus G Glycoproteins
K. Narayanan, M. Amaya, N. Tsang, R. Yin, A. Jays, C. C. Broder, D. Shukla, E. Procko
This paper identifies sequence changes in Ephrin-B2 that enhance its binding to henipavirus glycoproteins over Eph receptors, enabling the design of neutralizing decoy receptors.
bioRxiv · Apr 26, 2023Microbiology