Author

K. Narayanan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:plant (other)· 1

Frequent Co-Authors

D. Shukla· 2 shared E. Procko· 2 shared S. Makino· 2 shared A. Gluck· 1 shared A. Jays· 1 shared A. Nachshon· 1 shared A. T. Weigle· 1 shared A. Tamin· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPlant Biology

D. Shukla

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Author profile →

4 papers

Recent·Most cited

Deep mutational scanning reveals sequence to function constraints for SWEET family transporters

K. Narayanan, A. T. Weigle, L. Xu, X. Mi, C. Zhang, L.-Q. Chen, E. Procko, D. Shukla

This study uses deep mutational scanning to analyze sequence-function relationships in the plant SWEET transporter AtSWEET13, identifying mutations that enhance transport function and revealing constraints in transmembrane helix 4.

bioRxiv · Jun 28, 2024 · PreprintPlant Biology

The Sequence Basis for Selectivity of Ephrin-B2 Ligand for Eph Receptors and Pathogenic Henipavirus G Glycoproteins

K. Narayanan, M. Amaya, N. Tsang, R. Yin, A. Jays, C. C. Broder, D. Shukla, E. Procko

This paper identifies sequence changes in Ephrin-B2 that enhance its binding to henipavirus glycoproteins over Eph receptors, enabling the design of neutralizing decoy receptors.

bioRxiv · Apr 26, 2023Microbiology

Parsing the role of NSP1 in SARS-CoV-2 infection

T. Fisher, A. Gluck, K. Narayanan, M. Kuroda, A. Nachshon, J. C Hsu, P. J Halfmann, Y. Yahalom-Ronen, Y. Finkel, M. Schwartz, S. Weiss, C.-T. K Tseng, T. Israely, N. Paran, Y. Kawaoka, , N. Stern-Ginossar

This study investigates the role of SARS-CoV-2 nsp1 in host shutoff and immune evasion, finding it inhibits translation and induces mRNA degradation, and is critical for counteracting the IFN response.

bioRxiv · Mar 14, 2022Microbiology

Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient

J. Harcourt, A. Tamin, X. Lu, S. Kamili, S. Kumar Sakthivel, L. Wang, J. Murray, K. Queen, B. Lynch, B. Whitaker, Y. Tao, C. Paden, J. Zhang, Y. Li, A. Uehara, , N. J. Thornburg

The paper isolates and characterizes SARS-CoV-2 from the first US COVID-19 patient, showing high replication in Vero cells and depositing the strain for public use.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology