R. Yin

This study investigates how Formononetin reverses Osimertinib resistance in NSCLC cells by analyzing gene expression changes.

The paper shows that persistent infections increase the likelihood of autoimmune T cell activation by exceeding a quorum threshold through molecular mimicry.

This paper identifies sequence changes in Ephrin-B2 that enhance its binding to henipavirus glycoproteins over Eph receptors, enabling the design of neutralizing decoy receptors.

This study shows sustainable land management improves ecological and economic multifunctionality in agroecosystems, even under future climate conditions.

The paper uses single-cell transcriptomics to study cell fate transitions during early de novo shoot regeneration in Arabidopsis, identifying redifferentiation trajectories and regulatory factors.

This study introduces scStereo-seq, a method for single-cell spatial transcriptome profiling in Arabidopsis leaves, revealing cell type-specific spatial gene expression gradients and developmental trajectories.

This study uses a fluorescent SUMO biosensor to show that prostate cancer cells have higher and reversible cytosolic SUMO enrichment under stress compared to normal cells.

The paper determines the structural basis for recognition of two SARS-CoV-2 spike epitopes by T cell receptors, revealing insights into epitope specificity and variation.

The paper maps antibody recognition of SARS-CoV-2 spike RBD using computational structural analysis and identifies antibodies effective against viral variants.

This study shows that SARS-CoV-2 Spike protein activates macrophages and induces acute lung inflammation in mice.

CoV3D provides a database of coronavirus protein structures, including spike glycoprotein complexes, for vaccine and therapeutic design.

This study shows climate change and intensive land use reduce soil animal biomass through different pathways: climate change reduces body size, while land use decreases population size.

This study identifies O-GlcNAc transferase as a suppressor of hepatocyte necroptosis and liver fibrosis, using both human and mouse models.