KIF16B mediates anterograde transport and modulates lysosomal degradation of the HIV-1 envelope glycoprotein
N. Weaver, J. Hammonds, L. Ding, G. Lerner, K. Dienger-Stambaugh, P. Spearman
This study identifies KIF16B as a host motor protein that facilitates HIV-1 Env trafficking to the plasma membrane, prevents lysosomal degradation, and enhances viral particle incorporation and infectivity.
bioRxiv · Mar 1, 2023Microbiology