Cytosolic acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA
N. Zeaiter, L. Belot, V. Cunin, R. Abi Nahed, M. Tokarska-Schlattner, A. Le Gouellec, C. Petosa, S. Khochbin, U. Schlattner
The paper shows ACSS2 does not generate butyryl- or crotonyl-CoA from SCFAs, challenging previous assumptions about its substrate specificity.
bioRxiv · Dec 21, 2023 · PreprintBiochemistry